Glossary

Abrogate:
To suppress or prevent.

Mucous Membrane:
A thin layer that lines many cavities and structures in the body that are exposed to air in the environment, such as the nose, mouth, and lungs.

Gastrointestinal Tract:
The series of hollow organs, including the mouth, esophagus, stomach, small intestine, large intestine (colon), rectum, and anus, which break down and digest food and expel waste.

Esophagus:
The tube that carries food and liquids from the mouth to the stomach.

Urethra:
The tube leading from the bladder through which urine is carried from the body.

Larynx:
A tube-shaped organ in the neck that contains the vocal cords.

Bradykinin:
A naturally occurring peptide hormone that consists of nine amino acids and is formed locally in tissue. It is involved in the mediation of pain in the event of injury or inflammation. It increases the permeability of the vessels, dilates the blood vessels, and causes smooth muscle to contract. In Hereditary angioedema (HAE), bradykinin is the key mediator for the development of swelling.

Endothelium:
A layer of flat cells lining the closed internal spaces of the body, such as the inside of blood vessels and lymphatic vessels, and the heart.

Vasodilation:
A widening of the blood vessels that results in increased blood flow.